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Musculoskeletal comorbidities in cardiovascular disease, diabetes and respiratory disease: the impact on activity limitations

Not intended for use by persons under the age of 18

In that study, the effect size of trimetazidine on reducing oxidative stress was larger than daily exercise intervention, showing its potential as a powerful antioxidant

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doi:10.1155/2017/2549491

While the employed rodent model replicates key metabolic and histopathological features of the human condition, and the conservation of the identified target pathways between species supports the biological plausibility of our findings, several critical aspects remain to be fully addressed